Article
BMP-2 and cAMP elevation confer locus coeruleus neurons responsiveness to multiple neurotrophic factors.
Journal of neurobiology - 1 Mar 2002
Reiriz Julia, Holm Pontus C, Alberch Jordi, Arenas Ernest
Abstract excerpt
The locus coeruleus (LC) is a major target of several neurodegenerative disorders, including Parkinson's and Alzheimer's diseases. However, very little is known of the trophic requirements of LC neurons. In the present work, we have studied the biological activity of neurotrophic factors from dif...
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