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Article

Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia.

Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2002

Liu Hui, Heath Simon C, Sobin Christina, Roos J Louw, Galke Brandi L, Blundell Maude L, Lenane Marge, Robertson Brian, Wijsman Ellen M, Rapoport Judith L, Gogos Joseph A, Karayiorgou Maria

Abstract excerpt

The location of a schizophrenia susceptibility locus at chromosome 22q11 has been suggested by genome-wide linkage studies. Additional support was provided by the observation of a higher-than-expected frequency of 22q11 microdeletions in patients with schizophrenia and the demonstration that appr...

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Identifiers

PMID: 11891283
DOI: 10.1073/pnas.042700699
PMCID: PMC122590

Genes

PRODH2
DGCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11891283-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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