Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of Expression of<i>GADD45γ</i>, a Growth Inhibitory Gene, in Human Pituitary Adenomas: Implications for Tumorigenesis

1 Mar 2002

Abstract excerpt

The underlying molecular pathogenic mechanisms remain unknown in the majority of human pituitary tumors. GADD45 gamma is a member of a growth arrest and DNA damage-inducible gene family that functions in the negative regulation of cell growth. We have found that the mRNA expression of the GADD45 gamma gene is significantly different between normal human pituitary tissue and clinically nonfunctioning pituitary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Microtubule and mitosis dynamics
Share to Pituitary Gland Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11889197
DOI: 10.1210/jcem.87.3.8315

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of Expression of<i>GADD45γ</i>, a Growth Inhibitory Gene, in Human Pituitary Adenomas: Implications for TumorigenesisPMID 11889197Read ↗

Loss of expression of the growth inhibitory gene GADD45γ, in human pituitary adenomas, is associated with CpG island methylationSemantic proximity Read ↗

Identification of Growth Arrest and DNA-Damage-Inducible Gene β (GADD45β) as a Novel Tumor Suppressor in Pituitary Gonadotrope TumorsSemantic proximity Read ↗

A Pituitary-Derived MEG3 Isoform Functions as a Growth Suppressor in Tumor CellsSemantic proximity Read ↗

Selective Loss of MEG3 Expression and Intergenic Differentially Methylated Region Hypermethylation in the MEG3/DLK1 Locus in Human Clinically Nonfunctioning Pituitary AdenomasSemantic proximity Read ↗

The p15<sup>INK4b</sup>/p16<sup>INK4a</sup>/RB1 Pathway Is Frequently Deregulated in Human Pituitary AdenomasSemantic proximity Read ↗

The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors.Semantic proximity Read ↗

Characterization of human Gadd45, a p53-regulated protein.Semantic proximity Read ↗

Silencing of the Imprinted DLK1-MEG3 Locus in Human Clinically Nonfunctioning Pituitary AdenomasSemantic proximity Read ↗

The retinoblastoma gene in human pituitary tumors.Semantic proximity Read ↗

Subtraction hybridization identifies a transformation progression-associated gene <i>PEG</i> -3 with sequence homology to a growth arrest and DNA damage-inducible geneSemantic proximity Read ↗

Rare mutations of the Gs alpha subunit gene in human endocrine tumors. Mutation detection by polymerase chain reaction—primer-introduced restriction analysisSemantic proximity Read ↗

Genetic aspects of pituitary tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.