Article
Genotyping of human platelet antigen-1 by gene amplification and labelling in one system and automated fluorescence correlation spectroscopy.
British journal of haematology - 1 Mar 2002
Weber Stephanie, Hummel Stefan A, Weber Artur-Aron, Zirwes Rudolf F, Weiner Olaf H, Reuber Bernadette E
Abstract excerpt
Genotyping of human platelet antigen-1 (HPA-1) is required for the diagnosis and appropriate therapy of alloimmunization. Recently, the HPA-1 polymorphism has been identified as an inherited risk factor for thrombosis. Most currently used methods for HPA-1 genotyping have the disadvantage of time-consuming post-polymerase chain reaction (PCR) processes such as ligation (oligonucleotide ligation assay),...
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