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Article

Altered amelogenin self-assembly based on mutations observed in human X-linked amelogenesis imperfecta (AIH1).

The Journal of biological chemistry - 10 May 2002

Paine Michael L, Lei Ya-Ping, Dickerson Kenneth, Snead Malcolm L

Abstract excerpt

A hallmark of biological systems is a reliance on protein assemblies to perform complex functions. We have focused attention on mammalian enamel formation because it relies on a self-assembling protein complex to direct mineral habit. The principle protein of enamel is amelogenin, a 180-amino acid hydrophobic protein that self-assembles to form nanospheres. We have used independent technical methods, consisting...

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Identifiers

PMID: 11877393
DOI: 10.1074/jbc.M110473200
PMCID: PMC12931982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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