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Article

The prothrombin 20210A allele influences clinical manifestations of hemophilia A in patients with intron 22 inversion and without inhibitors.

Haematologica - 1 Mar 2002

Tizzano Eduardo F, Soria José Manuel, Coll Immaculada, Guzmán Blanca, Cornet Mónica, Altisent Carmen, Martorell Marta, Domenech Montserrat, del Río Elisabeth, Fontcuberta Jordi, Baiget Montserrat

Abstract excerpt

BACKGROUND AND OBJECTIVES: The modulation of disease severity in hemophilia A (HA) patients may be related to the co-inheritance of mutations in genes with a known thrombotic effect such as factor V Leiden (FVL) and prothrombin. In the Spanish population, the prothrombin 20210A (PT20210A) allele is the most prevalent genetic risk factor for venous thromboembolism. DESIGN AND METHODS: We investigated the presence...

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PMID: 11869940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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