Article
[The susceptible alleles on HLA-DRB 1 of type I diabetes in children in Harbin].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Aug 2000
Zhang H, Wang B, Zhao X, Sun J, Liang Z, Zhang D, Yang Z, Sun Y, Shen J
Abstract excerpt
OBJECTIVE: To evaluate association between type I diabetes in children and HLA-DRB1 alleles in Harbin. METHODS: Case-control method was employed, and the PCR-SSP technique was used to identify HLA-DRB1 alleles. RESULTS: The frequencies of DRB1 * 0301 and DR3/4 heterozygosity were significantly higher but the frequency of DR2 was significantly lower in cases than that in controls. In DR4 subtypes, the frequency of...
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