Article
Experimental non-transmissible marker vaccines for classical swine fever (CSF) by trans-complementation of E(rns) or E2 of CSFV.
Vaccine - 22 Feb 2002
van Gennip H G P, Bouma A, van Rijn P A, Widjojoatmodjo M N, Moormann R J M
Abstract excerpt
Three mutants with deletions in the E2 gene of the infectious DNA copy of the classical swine fever virus (CSFV) strain-C were constructed: one missing the B/C domain of CSFV-E2 between amino acids (aa) 693 and 746, one missing the A domain between aa 800 and 864, and one missing the complete E2 between aa 689 and 1062. All three CSFV-E2 deletion mutants were unable to generate viable virus, indicating that each...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
