Article
Pigs immunized with a novel E2 subunit vaccine are protected from subgenotype heterologous classical swine fever virus challenge.
BMC veterinary research - 9 Sept 2016
Madera Rachel, Gong Wenjie, Wang Lihua, Burakova Yulia, Lleellish Karen, Galliher-Beckley Amy, Nietfeld Jerome, Henningson Jamie, Jia Kaimin, Li Ping, Bai Jianfa, Schlup John, McVey Scott, Tu Changchun, Shi Jishu
Abstract excerpt
BACKGROUND: Classical swine fever (CSF) or hog cholera is a highly contagious swine viral disease. CSF endemic countries have to use routine vaccination with modified live virus (MLV) vaccines to prevent and control CSF. However, it is impossible to serologically differentiate MLV vaccinated pigs from those infected with CSF virus (CSFV). The aim of this study is to develop a one-dose E2-subunit vaccine that can...
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