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Article

Development of a marker vaccine candidate against classical swine fever based on the live attenuated vaccine C-strain.

Veterinary microbiology - 1 Aug 2020

Han Yuying, Xie Libao, Yuan Mengqi, Ma Yuteng, Sun Huimin, Sun Yuan, Li Yongfeng, Qiu Hua-Ji

Abstract excerpt

Classical swine fever (CSF) is a highly contagious and economically damaging disease. Classical swine fever virus (CSFV) lapinized vaccine C-strain against CSF worldwide lacks the capacity for the serological differentiation between infected and vaccinated animals (DIVA). To develop a marker C-strain complying with the DIVA principle, we generated and evaluated mutants rHCLV-E2F117A, rHCLV-E2G119A, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32768202
DOI: 10.1016/j.vetmic.2020.108741

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