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Article

The Histone Deacetylase Inhibitor Trichostatin A Derepresses the Telomerase Reverse Transcriptase (hTERT) Gene in Human Cells

1 Mar 2002

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Share to Genomics and Chromatin Dynamics
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Share to Telomeres, Telomerase, and Senescence

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 11855854
DOI: 10.1006/excr.2001.5462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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The Histone Deacetylase Inhibitor Trichostatin A Derepresses the Telomerase Reverse Transcriptase (hTERT) Gene in Human CellsPMID 11855854Read ↗

Histone Deacetylation Is Involved in the Transcriptional Repression of hTERT in Normal Human CellsSemantic proximity Read ↗

Increased alternative lengthening of telomere phenotypes of telomerase-negative immortal cells upon trichostatin--a treatment.Semantic proximity Read ↗

Telomerase activation by histone deacetylase inhibitor in normal cellsSemantic proximity Read ↗

Gene expression profiling after treatment with the histone deacetylase inhibitor trichostatin A reveals altered expression of both pro- and anti-apoptotic genes in pancreatic adenocarcinoma cellsSemantic proximity Read ↗

The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line modelSemantic proximity Read ↗

A Histone Deacetylase Inhibitor, Trichostatin A, Enhances Radiosensitivity by Abrogating G2/M Arrest in Human Carcinoma CellsSemantic proximity Read ↗

Attenuated DNA Damage Repair by Trichostatin A through BRCA1 SuppressionSemantic proximity Read ↗

Depletion of mutant p53 and cytotoxicity of histone deacetylase inhibitors.Semantic proximity Read ↗

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.Semantic proximity Read ↗

Evidence for a Relief of Repression Mechanism for Activation of the Human Telomerase Reverse Transcriptase PromoterSemantic proximity Read ↗

Effect of trichostatin A on cell growth and expression of cell cycle- and apoptosis-related molecules in human gastric and oral carcinoma cell linesSemantic proximity Read ↗

Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cellsSemantic proximity Read ↗

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