Article
Genetic polymorphisms of metabolic enzymes-CYP1A1, CYP2D6, GSTM1, and GSTT1, and gastric carcinoma susceptibility.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2011
Luo Ya-Ping, Chen Han-Chun, Khan Md Asaduzzaman, Chen Fang-Zhi, Wan Xin-Xing, Tan Bo, Ou-Yang Fang-Dan, Zhang Dian-Zheng
Abstract excerpt
Genetic polymorphisms in metabolic enzymes are associated with numerous cancers. In this study, the relationships between genetic polymorphisms of phase I metabolic enzymes including cytochrome P450 1A1 (CYP1A1), CYP2D6 and phase II metabolic enzymes such as glutathione S-transferase M1 (GSTM1) and GSTT1 and gastric carcinoma susceptibility were investigated. Genomic DNA was isolated from the peripheral blood of...
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