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Article

Influence of the alternative sigma(28) factor on virulence and flagellum expression of Legionella pneumophila.

Infection and immunity - 1 Mar 2002

Heuner Klaus, Dietrich Claudia, Skriwan Carina, Steinert Michael, Hacker Jörg

Abstract excerpt

The fliA gene of Legionella pneumophila encoding the alternative sigma(28) factor was inactivated by introducing a kanamycin resistance cassette. Electron microscopy and Western blot analysis revealed that the fliA mutant strain is aflagellate and expresses no flagellin. Reporter gene assays indicated that the flaA promoter is not active in the fliA mutant strain. The fliA mutant strain multiplied less...

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Identifiers

PMID: 11854250
DOI: 10.1128/IAI.70.3.1604-1608.2002
PMCID: PMC127743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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