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Article

Molecular characterization of type III secretion signals via analysis of synthetic N-terminal amino acid sequences.

Molecular microbiology - 1 Jan 2002

Lloyd Scott A, Sjöström Michael, Andersson Sara, Wolf-Watz Hans

Abstract excerpt

Yersinia species utilize a type III secretion system to inject toxins, called Yops (Yersinia outer proteins), into eukaryotic cells. The N-termini of the Yops serve as type III secretion signals, but they do not share a consensus sequence. To simplify the analysis of type III secretion signals, we replaced amino acids 2-8 of the secreted protein YopE with all permutations (27 or 128) of synthetic...

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PMID: 11849536
DOI: 10.1046/j.1365-2958.2002.02738.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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