Article
Allelic frequencies of six polymorphic markers for risk of prostate cancer.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Feb 2002
Ribeiro M L, Santos A, Carvalho-Salles A B, Hackel C
Abstract excerpt
The aim of the present study was to evaluate the distribution of polymorphisms for the androgen receptor (AR) (CAG, StuI, GGN), SRD5A2 (Ala49Thr, Val89Leu) and CYP17 (MspA1) genes that are considered to be relevant for risk of prostate cancer. We studied 200 individuals from two cities in the State of São Paulo, by PCR, PCR-RFLP and ASOH techniques. The allelic frequencies of the autosomal markers and the StuI...
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