Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of mast-cell tryptase-expressing peripheral blood cells as basophils.

The Journal of allergy and clinical immunology - 1 Feb 2002

Foster Barbara, Schwartz Lawrence B, Devouassoux Gilles, Metcalfe Dean D, Prussin Calman

Abstract excerpt

BACKGROUND: Mast-cell tryptase is a protease with proinflammatory activity, the expression of which by peripheral blood leukocytes (PBLs) has not been fully characterized. OBJECTIVE: We examined tryptase expression in human PBLs to further characterize this tryptase-expressing cell population for lineage and disease association. METHODS: PBLs were fixed, permeabilized, stained with antibodies to tryptase and a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basophils
Share to Hypersensitivity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Mast Cells

Share to Mastocytosis

Share to Serine Endopeptidases

Share to Staining and Labeling

Share to Tryptases

Source

Identifiers

PMID: 11842299
DOI: 10.1067/mai.2002.121454

Genes

FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of mast-cell tryptase-expressing peripheral blood cells as basophils.PMID 11842299Read ↗

Hemopoietic cells with features of the mast cell and basophil lineages and their potential role in allergy.Semantic proximity Read ↗

Differentiation of human basophils: an overview of recent advances and pending questions.Semantic proximity Read ↗

Differential expression of mast cell characteristics in human myeloid cell lines.Semantic proximity Read ↗

Mast Cell-Lineage Versus Basophil Lineage Involvement in Myeloproliferative and Myelodysplastic Syndromes: Diagnostic Role of Cell-Immunopheno typingSemantic proximity Read ↗

Analysis of the lineage relationship between mast cells and basophils using the c-kit D816V mutation as a biologic signature.Semantic proximity Read ↗

Human mast cells arise from a common circulating progenitor.Semantic proximity Read ↗

Immunophenotypic characterization of human basophils and mast cells.Semantic proximity Read ↗

A phenotypic screening approach in cord blood-derived mast cells to identify anti-inflammatory compounds.Semantic proximity Read ↗

Expression of alpha-tryptase and beta-tryptase by human basophils.Semantic proximity Read ↗

Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype.Semantic proximity Read ↗

Mast cell lines HMC‐1 and LAD2 in comparison with mature human skin mast cells – drastically reduced levels of tryptase and chymase in mast cell linesSemantic proximity Read ↗

The phenotype of human eosinophils, basophils, and mast cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.