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Article

Interactive effect of cytochrome P450 17alpha-hydroxylase and dopamine D3 receptor gene polymorphisms on abnormal involuntary movements in chronic schizophrenia.

Biological psychiatry - 1 Feb 2002

Segman Ronnen H, Heresco-Levy Uriel, Yakir Avi, Goltser Tanya, Strous Rael, Greenberg David A, Lerer Bernard

Abstract excerpt

BACKGROUND: Tardive dyskinesia is a chronic adverse effect of anti psychotic drugs, where association with a polymorphic site in the dopamine D3 receptor gene has been previously reported. Cytochrome P 450 17alpha-hydroxylase activity has been implicated with modulation of central dopamine release as well as neuroprotection. We investigated the association of a T -->C variation in the cytochrome P 450...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to Dyskinesia, Drug-Induced

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Share to Steroid 17-alpha-Hydroxylase

Source

Identifiers

PMID: 11839369
DOI: 10.1016/s0006-3223(01)01302-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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