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Article

Inositol and folate resistant neural tube defects

1 Feb 2002

Abstract excerpt

Folic acid supplementation is widely used to prevent neural tube defects (NTDs).1,2 Yet not all cases of NTD appear to respond to folic acid. For instance, in the randomised controlled trial sponsored by the Medical Research Council,1 six NTD recurrences were noted among 593 women (1%) who received full folic acid supplementation, compared with 21 recurrences among 602 unsupplemented pregnancies (3.5%). Hence, in...

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PMID: 11836374
DOI: 10.1136/jmg.39.2.e5

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