Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rh genotyping: avoiding false-negative and false-positive results among individuals of African ancestry.

American journal of hematology - 1 Jan 2002

Ekman G C, Billingsly R, Hessner M J

Abstract excerpt

High homology, variant alleles, and silent alleles have made the development of completely reliable genotyping assays for the RHD and RHC alleles difficult. An RHD pseudogene (RHDPsi) possessing a 37-bp insertion within exon 4 is common among serologically RhD-negative individuals of African descent and generates false-positive results in previously reported RhD genotyping assays. Genotyping RhC is problematic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies
Share to Black People
Share to Cytosine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to False Negative Reactions

Share to False Positive Reactions

Share to Immunophenotyping

Share to Rh-Hr Blood-Group System

Share to Rh Isoimmunization

Source

Identifiers

PMID: 11835329
DOI: 10.1002/ajh.10013

Genes

RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rh genotyping: avoiding false-negative and false-positive results among individuals of African ancestry.PMID 11835329Read ↗

RHC and RHc genotyping in different ethnic groups.Semantic proximity Read ↗

The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in africans with the Rh D-negative blood group phenotype.Semantic proximity Read ↗

Specificity and sensitivity of RHD genotyping methods by PCR-based DNA amplification.Semantic proximity Read ↗

Two new RHD alleles with deletions spanning multiple exons.Semantic proximity Read ↗

Presence of the RHD pseudogene and the hybrid RHD-CE-D(s) gene in Brazilians with the D-negative phenotype.Semantic proximity Read ↗

RHCE*ceAG (254C>G, Ala85Gly) is prevalent in blacks, encodes a partial ce-phenotype, and is associated with discordant RHD zygosity.Semantic proximity Read ↗

Rapid Rh D genotyping by polymerase chain reaction-based amplification of DNA.Semantic proximity Read ↗

Evidence of genetic diversity underlying Rh D-, weak D (Du), and partial D phenotypes as determined by multiplex polymerase chain reaction analysis of the RHD gene.Semantic proximity Read ↗

Clinically relevant RHD-CE genotypes in patients with sickle cell disease and in African Brazilian donors.Semantic proximity Read ↗

The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in Africans with the Rh D-negative blood group phenotypeSemantic proximity Read ↗

Estimating the serological underrecognition of patients with weak or partial RHD variants.Semantic proximity Read ↗

RhD status of a fetus at risk for haemolytic disease with a discrepant maternal DNA-based RhD genotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.