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Article

Large-scale genotyping by mass spectrometry: experience, advances and obstacles.

Current opinion in chemical biology - 1 Feb 2002

Lechner Doris, Lathrop G Mark, Gut Ivo G

Abstract excerpt

Single nucleotide polymorphism (SNP) genotyping has become a key technology for genetic studies. In recent years, matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry has emerged as a very powerful method for SNP genotyping. Here, we discuss our experience in implementing a high-throughput SNP genotyping facility based on MALDI, and the issues encountered in adapting this to...

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Share to Genetic Testing
Share to Genotype
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Sequence Analysis, DNA

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Identifiers

PMID: 11827820
DOI: 10.1016/s1367-5931(01)00290-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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