Article
Host association of Borrelia burgdorferi sensu lato--the key role of host complement.
Trends in microbiology - 1 Feb 2002
Kurtenbach Klaus, De Michelis Simona, Etti Susanne, Schäfer Stefanie M, Sewell Henna-Sisko, Brade Volker, Kraiczy Peter
Abstract excerpt
Borrelia burgdorferi sensu lato (s.l.), the tick-borne agent of Lyme borreliosis, is a bacterial species complex comprising 11 genospecies. Here, we discuss whether the delineation of genospecies is ecologically relevant. We provide evidence that B. burgdorferi s.l. is structured ecologically into distinct clusters that are host specific. An immunological model for niche adaptation is proposed that suggests the...
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