Article
Human and murine phenotypes associated with defects in cation-chloride cotransport.
Annual review of physiology - 1 Jan 2002
Delpire Eric, Mount David B
Abstract excerpt
The diuretic-sensitive cotransport of cations with chloride is mediated by the cation-chloride cotransporters, a large gene family encompassing a total of seven Na-Cl, Na-K-2Cl, and K-Cl cotransporters, in addition to two related transporters of unknown function. The cation-chloride cotransporters perform a wide variety of physiological roles and differ dramatically in patterns of tissue expression and cellular...
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