Article
Prefrontal cortical volume in childhood-onset major depression: preliminary findings.
Archives of general psychiatry - 1 Feb 2002
Nolan Carla L, Moore Gregory J, Madden Rachel, Farchione Tiffany, Bartoi Marla, Lorch Elisa, Stewart Carol M, Rosenberg David R
Abstract excerpt
BACKGROUND: Abnormalities in the prefrontal cortex have been implicated in the pathogenesis of major depressive disorder (MDD). To our knowledge, no prior study has examined prefrontal cortical anatomy in pediatric patients with MDD near the onset of illness before receiving treatment. METHODS: Volumetric magnetic resonance imaging studies were conducted in 22 psychotropic-naive patients with MDD, aged 9 to 17...
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