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Article

CST3 genotype associated with exudative age related macular degeneration.

The British journal of ophthalmology - 1 Feb 2002

Zurdel Jan, Finckh Ulrich, Menzer Gunnar, Nitsch Roger M, Richard Gisbert

Abstract excerpt

AIMS: To determine whether allelic variants of the cystatin C gene CST3 are genetically associated with exudative age related macular degeneration (ARMD). Cystatin C is a cysteine protease inhibitor that regulates the activity of cathepsin S, a protease with central regulatory functions in retinal pigment epithelial cells. METHODS: CST3 of 167 patients with exudative ARMD was genotyped by using polymerase chain...

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Source

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Identifiers

PMID: 11815350
DOI: 10.1136/bjo.86.2.214
PMCID: PMC1771004

Genes

CST3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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