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Article

TGFbeta1 allele association with asthma severity.

Human genetics - 1 Dec 2001

Pulleyn L J, Newton R, Adcock I M, Barnes P J

Abstract excerpt

Transforming growth factor beta1 (TGFbeta1) is a multifunctional cytokine involved in pro- and anti-inflammatory pathways and is expressed in several cell types. Subepithelial fibrosis is one of the principle features of airway remodelling in asthma and is increased in severe patients. TGFbeta1 is implicated in fibrosis, including the deposition of extracellular matrix proteins. TGFbeta1 mRNA levels in...

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Source

Identifiers

PMID: 11810274
DOI: 10.1007/s00439-001-0617-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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