Article
Genes for mevalonate biosynthesis in Phycomyces.
Molecular genetics and genomics : MGG - 1 Jan 2002
Ruiz-Albert J, Cerdá-Olmedo E, Corrochano L M
Abstract excerpt
Terpenoids or isoprenoids constitute a vast family of organic compounds that includes sterols and carotenoids. The terpenoids in many organisms share early steps in their biosynthesis, including the synthesis of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) and its conversion to mevalonate. We have cloned and characterised the genes hmgS for HMG-CoA synthase and hmgR for HMG-CoA reductase from the Zygomycete...
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