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Article

Assembly and function of AP-3 complexes in cells expressing mutant subunits.

The Journal of cell biology - 21 Jan 2002

Peden Andrew A, Rudge Rachel E, Lui Winnie W Y, Robinson Margaret S

Abstract excerpt

The mouse mutants mocha and pearl are deficient in the AP-3 delta and beta3A subunits, respectively. We have used cells from these mice to investigate both the assembly of AP-3 complexes and AP-3 function. In mocha cells, the beta3 and mu3 subunits coassemble into a heterodimer, whereas the sigma3 subunit remains monomeric. In pearl cells, the delta and sigma3 subunits coassemble into a heterodimer, whereas mu3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11807095
DOI: 10.1083/jcb.200107140
PMCID: PMC2199225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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