Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MTR discloses subtle changes in the normal-appearing tissue from relatives of patients with MS.

Neurology - 22 Jan 2002

Siger-Zajdel Malgorzata, Filippi Massimo, Selmaj Krzysztof

Abstract excerpt

The presence of normal-appearing brain tissue (NABT) changes was investigated in 30 first-degree relatives of patients with MS, using magnetization transfer ratio (MTR) histograms. When compared with controls, relatives of patients with familial (p = 0.01) and sporadic (p = 0.01) MS had lower NABT MTR histogram peak heights. This study suggests a reduction of truly normal NABT in asymptomatic relatives of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Family
Share to MTR gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Magnetic Resonance Imaging

Share to Multiple Sclerosis

Source

Identifiers

PMID: 11805268
DOI: 10.1212/wnl.58.2.317

Genes

MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

MTR discloses subtle changes in the normal-appearing tissue from relatives of patients with MS.PMID 11805268Read ↗

Magnetisation transfer ratio analysis of normal appearing white matter in patients with familial and sporadic multiple sclerosis.Semantic proximity Read ↗

Magnetization transfer imaging to monitor the evolution of MS: a 1-year follow-up study.Semantic proximity Read ↗

MRI characteristics of familial and sporadic multiple sclerosis patients.Semantic proximity Read ↗

Comparison of MS clinical phenotypes using conventional and magnetization transfer MRI.Semantic proximity Read ↗

Prevalence of radiologically isolated syndrome and white matter signal abnormalities in healthy relatives of patients with multiple sclerosis.Semantic proximity Read ↗

Multiple sclerosis and subclinical neuropathology in healthy individuals with familial risk: A scoping review of MRI studies.Semantic proximity Read ↗

MPRAGE-derived quantitative T <sub>1</sub> mapping to assess diffuse white matter alterations in multiple sclerosisSemantic proximity Read ↗

Magnetization transfer imaging in 'premanifest' Huntington's disease.Semantic proximity Read ↗

Quantitative susceptibility mapping in multiple sclerosis.Semantic proximity Read ↗

Unexpected multiple sclerosis: follow-up of 30 patients with magnetic resonance imaging and clinical conversion profile.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.