Article
Regulation of protein kinase C in Escherichia coli K1 invasion of human brain microvascular endothelial cells.
The Journal of biological chemistry - 5 Apr 2002
Sukumaran Sunil K, Prasadarao Nemani V
Abstract excerpt
Escherichia coli is one of the most important pathogens involved in the development of neonatal meningitis in many parts of the world. Traversal of E. coli across the blood-brain barrier is a crucial event in the pathogenesis of E. coli meningitis. Our previous studies have shown that outer membrane protein A (OmpA) expression is necessary in E. coli for a mechanism involving actin filaments in its passage...
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