Article
Outer membrane protein A (OmpA) of Cronobacter sakazakii binds fibronectin and contributes to invasion of human brain microvascular endothelial cells.
Foodborne pathogens and disease - 1 May 2009
Nair Manoj Kumar Mohan, Venkitanarayanan Kumar, Silbart Lawrence K, Kim Kwang Sik
Abstract excerpt
Cronobacter sakazakii is an emerging foodborne pathogen that causes severe meningitis and meningoencephalitis in neonates. Currently there is a dearth of information available on the virulence factors of C. sakazakii and the pathogenic mechanisms involved in its neonatal infections. The invasion and translocation of the blood-brain barrier formed by brain microvascular endothelial cells (BMEC) is critical in the...
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