Article
Variation at the angiotensin-converting enzyme gene and angiotensinogen gene loci in relation to blood pressure.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 1996
Kiema T R, Kauma H, Rantala A O, Lilja M, Reunanen A, Kesäniemi Y A, Savolainen M J
Abstract excerpt
To investigate whether the polymorphisms in the angiotensin-converting enzyme and angiotensinogen genes are associated with hypertension, we carried out a case-control study of 508 hypertensive and 523 control subjects randomly selected from the Social Insurance Institution register. The cohorts...
Topics
- Adult
- Angiotensinogen
- Blood Pressure
- Cohort Studies
- Female
- Finland
- Genes, ras
- Genetic Variation
- Genetics, Population
- Genotype
- Humans
- Hypertension
- Male
- Middle Aged
- Peptidyl-Dipeptidase A
- Polymerase Chain Reaction
- Prevalence
- Random Allocation