Article
Adaptations of linkage and association methods for the study of asthma, a complex trait.
Genetic epidemiology - 1 Jan 2001
Bosken C H, Ko Y C, Shete S, Wang T N, Chen J, Amos C I, Cheng L S
Abstract excerpt
Early studies that found significant linkage between markers on 5q and asthma and IgE have not been reproduced. In an attempt to improve the power of these studies we performed a variance components linkage analysis and transmission-disequilibrium tests (TDT) with haplotypes using markers on 5q, using the Southampton and Perth data sets supplied by GAW. The linkage analysis with covariates revealed a maximum lod...
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