Article
Selection of single nucleotide polymorphisms for association studies in candidate genes.
Genetic epidemiology - 1 Jan 2001
Génin E
Abstract excerpt
Comparison of polymorphic sites such as single nucleotide polymorphisms (SNPs) within a gene between cases and controls may be useful for establishing a role of this gene in disease susceptibility. The approach includes two steps: the first step is the discovery of the different SNPs within the candidate gene and the second step is the association testing per se that can be done on the entire set of sites...
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