Article
Life after the screen: making sense of many P-values.
Genetic epidemiology - 1 Jan 2001
Schmidt S, Shao Y, Hauser E R, Slifer S H, Martin E R, Scott W K, Speer M C, Pericak-Vance M A
Abstract excerpt
A multiple analytic approach may be useful for analyzing complex traits since different methods extract both similar and distinct, but complementary pieces of information from genome screen data on extended pedigrees. We examined the usefulness of combining p-values both across methods and across adjacent markers, taking into account the observed correlation structure among these p-values. To this end, we...
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