Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differentially amplified chromosome 12 sequences in low‐ and high‐grade osteosarcoma

16 Nov 2001

Abstract excerpt

Most osteosarcomas are highly aggressive malignancies characterized by a complex pattern of chromosome abnormalities. However, a subgroup of low-grade, parosteal tumors exhibits a relatively simple aberration pattern dominated by ring chromosomes carrying amplified material from chromosome 12. To assess whether sequences from this chromosome were differentially amplified in low- and high-grade osteosarcomas, copy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Genomics and Chromatin Dynamics
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11793439
DOI: 10.1002/gcc.1219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differentially amplified chromosome 12 sequences in low‐ and high‐grade osteosarcomaPMID 11793439Read ↗

Characterization of the 12q15 MDM2 and 12q13-14 CDK4 amplicons and clinical correlations in osteosarcoma.Semantic proximity Read ↗

Genomic and clinical analyses of 2p24 and 12q13‐q14 amplification in alveolar rhabdomyosarcoma: A report from the Children's Oncology GroupSemantic proximity Read ↗

Array‐comparative genomic hybridization of central chondrosarcomaSemantic proximity Read ↗

Analysis of SAS Gene and CDK4 and MDM2 Proteins in Low-Grade OsteosarcomaSemantic proximity Read ↗

Amplification at 12q13-14 in human malignant gliomas is frequently accompanied by loss of heterozygosity at loci proximal and distal to the amplification site.Semantic proximity Read ↗

Restricted 12p amplification and RAS mutation in human germ cell tumors of the adult testis.Semantic proximity Read ↗

A translocation t(6;14) in two cases of leiomyosarcoma: Molecular cytogenetic and array-based comparative genomic hybridization characterization.Semantic proximity Read ↗

Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomasSemantic proximity Read ↗

Genomic signatures of chromosomal instability and osteosarcoma progression detected by high resolution array CGH and interphase FISHSemantic proximity Read ↗

Genetic imbalances revealed by comparative genomic hybridization in osteosarcomasSemantic proximity Read ↗

DNA sequence copy number increase at 8q: A potential new prognostic marker in high-grade osteosarcomaSemantic proximity Read ↗

Frequency and Implications of Chromosome 8 and 12 Gains in Ewing SarcomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.