Article
High frequency of epithelial chimerism in liver transplants demonstrated by microdissection and STR-analysis.
Hepatology (Baltimore, Md.) - 1 Jan 2002
Kleeberger Wolfram, Rothämel Thomas, Glöckner Sabine, Flemming Peer, Lehmann Ulrich, Kreipe Hans
Abstract excerpt
It has recently been shown that epithelial cells derived from stem cells originating outside the liver are integrated into liver allografts. Whether epithelial intragraft chimerism protects transplants from rejection or chronic transplant dysfunction, and whether it interferes with recurrence of primary liver disease, is not known. Twenty-seven sequential biopsies derived from 9 liver-transplant recipients were...
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