Article
Clinical significance of molecular expression profiles of Hürthle cell tumors of the thyroid gland analyzed via tissue microarrays.
The American journal of pathology - 1 Jan 2002
Hoos Axel, Stojadinovic Alexander, Singh Bhuvanesh, Dudas Maria E, Leung Denis H Y, Shaha Ashok R, Shah Jatin P, Brennan Murray F, Cordon-Cardo Carlos, Ghossein Ronald
Abstract excerpt
Hürthle cell tumors are rare thyroid neoplasms for which disease biology is poorly understood and diagnosis of carcinoma can be challenging. The aim of the study was to characterize molecular expression profiles of Hürthle cell tumors and to determine the clinical significance of identified phenotypes. Paraffin-embedded tissue cores of normal thyroid (n = 18), and histopathologically well-defined Hürthle cell...
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