Article
Altered cell-type proportioning in Dictyostelium lacking adenosine monophosphate deaminase.
Developmental biology - 1 Jan 2002
Chae Soo-Cheon, Fuller Danny, Loomis William F
Abstract excerpt
The proportions of prespore and prestalk cells in Dictyostelium discoideum are regulated so that they are size invariant and can adjust when the ratio is perturbed. We have found that disruption of the gene amdA that encodes AMP deaminase results in a significantly increased proportion of prestalk cells. Strains lacking AMP deaminase form short, thick stalks and glassy sori with less than 5% the normal number of...
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