Article
[Effects of overexpression of p21WAF1/CIP1 on the malignant phenotype and apoptosis of human hepatocellular carcinoma cells].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Mar 1999
Yang F, Wang W
Abstract excerpt
OBJECTIVE: To study the effects of overexpression of p21WAF1/CIP1 on the malignant phenotype and apoptosis of human hepatocellular carcinoma cells. METHODS: p21WAF1/CIP1 gene was transfected into a human hepatocellular carcinoma cell line, HCC-9204 with p53 mutation. Flow cytometry (FLC), transmission electron microscopy (EM) and DNA electrophoresis were used to identity apoptosis. RESULTS: The transfected...
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