Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The significance of nucleotide repeat sequences in FVIII gene for detecting hemophilia A carriers].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Oct 2001

Long G, Zhu C, Liu J

Abstract excerpt

OBJECTIVE: To detect the carriers in hemophilia A(HA) families by haplotype analysis of the microsatellite polymorphisms at intron 13 [13(CA)n] and 22[22(GT)n(AG)n] in the factor VIII (FVIII) gene. METHOD: Multi-PCR amplification of 13(CA)n and 22(GT)n(AG)n combined with silver staining were used. RESULTS: In 35 HA families, 11 had HA history. There were 21 female members in the 11 HA families and all of them...

Topics

Alleles
DNA
Factor VIII
Family Health
Female
Gene Frequency
Haplotypes
Hemophilia A
Heterozygote
Humans
Male
Pedigree

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 11769673

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The significance of nucleotide repeat sequences in FVIII gene for detecting hemophilia A carriers].PMID 11769673Read ↗

[A study on the (CA)n in FVIII gene in Han ethnic group in Guangxi Zhuang Autonomous Region by amplification polymorphisms combined with silver staining].Semantic proximity Read ↗

[Mutation screening of the F VIII gene in 10 hemophilia A families].Semantic proximity Read ↗

[Application of STR genetic marker system in the detection of hemophilia A carriers in Guangxi, China].Semantic proximity Read ↗

[Application studies on the gene diagnosis and carrier detection of hemophilia A by using polymerase chain reaction-conformation sensitive gel electrophoresis].Semantic proximity Read ↗

[Gene diagnosis for hemophilia a using A combination of 4 techniques].Semantic proximity Read ↗

[Detection and analysis of factor VIII exon 14 mutation in severe hemophilia A patients].Semantic proximity Read ↗

[Gene diagnosis of hemophilia B by multiple STR analysis].Semantic proximity Read ↗

Analysing two dinucleotide repeats of FVIII gene in Iranian population.Semantic proximity Read ↗

[Clinical application of chromosome haplotype analysis and mutation analysis to the diagnosis of Wilson's disease].Semantic proximity Read ↗

[Relationship between genotypes and clinical phenotypes in patients from 7 hemophilia A families].Semantic proximity Read ↗

[The St14 (DXS 52) VNTR in a Guangdong Han population and detection of hemophilia A carriers].Semantic proximity Read ↗

Haemophilia A diagnosis by automated fluorescent DNA detection of ten factor VIII intron 13 dinucleotide repeat alleles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.