Article
[Application of STR genetic marker system in the detection of hemophilia A carriers in Guangxi, China].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 1 Dec 2012
Zhou Jun-Li, Wei Hong-Ying, Wu Hua, Hu Yan-Ling, Liang Wei-Ling
Abstract excerpt
OBJECTIVE: To establish a fast and simple genetic diagnosis technique based on a reliable, short tandem repeat (STR) genetic marker system for the detection of hemophilia A carriers in Guangxi, China. METHODS: Fluorescent PCR and capillary electrophoresis were used for allele genotyping at three intragenic/extragenic STR loci (F8Int13, DXS1073, and DXS9901) of FVIII gene in the members of 10 hemophilia A families...
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