Article
Immunohistochemical detection of malondialdehyde-DNA adducts in human oral mucosa cells
1 Jan 2002
Abstract excerpt
Malondialdehyde (MDA) is a major lipid peroxidation product that is mutagenic and tumorigenic. MDA-modified DNA adducts have been detected in animal and human tissues and may be a marker of human cancer risk. An immunohistochemical method, using a previously generated monoclonal antibody specific for MDA-DNA adducts, has been developed for the detection and quantification of DNA damage in human oral mucosa cells....
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