Article
Crystallization and preliminary X-ray crystallographic studies of a mutant of ribosome recycling factor from Escherichia coli, Arg132Gly.
Acta crystallographica. Section D, Biological crystallography - 1 Jan 2002
Nakano Hiroaki, Uchiyama Susumu, Yoshida Takuya, Ohkubo Tadayasu, Kato Hiroaki, Yamagata Yuriko, Kobayashi Yuji
Abstract excerpt
Ribosome recycling factor (RRF) plays a central role during the recycling of ribosomes in the final step of protein biosynthesis in prokaryotes and is therefore a favourable target for the development of new antibiotics. The crystal structure of Escherichia coli RRF has been reported to have an open L-shaped conformation, while other RRFs from thermophilic bacteria have a strict L-shaped conformation [Yun et al....
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