Article
Omapatrilat versus lisinopril: efficacy and neurohormonal profile in salt-sensitive hypertensive patients.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 2001
Campese V M, Lasseter K C, Ferrario C M, Smith W B, Ruddy M C, Grim C E, Smith R D, Vargas R, Habashy M F, Vesterqvist O, Delaney C L, Liao W C
Abstract excerpt
Omapatrilat, a vasopeptidase inhibitor, simultaneously inhibits neutral endopeptidase and ACE. The efficacy and hormonal profile of omapatrilat and lisinopril were compared in salt-sensitive hypertensive patients. On enrollment, antihypertensive medications were withdrawn, and patients received a single-blind placebo. On day 15, salt-sensitivity determinations were made. Salt-sensitive hypertensive patients...
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