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Article

SEK-1 MAPKK mediates Ca2+ signaling to determine neuronal asymmetric development in Caenorhabditis elegans.

EMBO reports - 1 Jan 2002

Tanaka-Hino Miho, Sagasti Alvaro, Hisamoto Naoki, Kawasaki Masato, Nakano Shunji, Ninomiya-Tsuji Jun, Bargmann Cornelia I, Matsumoto Kunihiro

Abstract excerpt

The mitogen-activated protein kinase (MAPK) pathway is a highly conserved signaling cascade that converts extracellular signals into various outputs. In Caenorhabditis elegans, asymmetric expression of the candidate odorant receptor STR-2 in either the left or the right of two bilaterally symmetrical olfactory AWC neurons is regulated by axon contact and Ca2+ signaling. We show that the MAPK kinase (MAPKK) SEK-1...

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Identifiers

PMID: 11751572
DOI: 10.1093/embo-reports/kvf001
PMCID: PMC1083920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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