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Article

The microprotein Minion controls cell fusion and muscle formation.

Nature communications - 1 Jun 2017

Zhang Qiao, Vashisht Ajay A, O'Rourke Jason, Corbel Stéphane Y, Moran Rita, Romero Angelica, Miraglia Loren, Zhang Jia, Durrant Eric, Schmedt Christian, Sampath Srinath C, Sampath Srihari C

Abstract excerpt

Although recent evidence has pointed to the existence of small open reading frame (smORF)-encoded microproteins in mammals, their function remains to be determined. Skeletal muscle development requires fusion of mononuclear progenitors to form multinucleated myotubes, a critical but poorly understood process. Here we report the identification of Minion (microprotein inducer of fusion), a smORF encoding an...

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Identifiers

PMID: 28569745
DOI: 10.1038/ncomms15664
PMCID: PMC5461507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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