Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening breast cancer patients for ATM mutations and polymorphisms by using denaturing high-performance liquid chromatography.

Environmental and molecular mutagenesis - 1 Jan 2001

Atencio D P, Iannuzzi C M, Green S, Stock R G, Bernstein J L, Rosenstein B S

Abstract excerpt

All 62 coding exons of the ATM gene, along with 10-20 bases of the intronic region flanking each exon, were screened for DNA base sequence alterations by using denaturing high-performance liquid chromatography (DHPLC) in a series of 52 breast cancer patients. Six (12%) of these patients exhibited a total of eight different novel germ-line mutations that do not represent common polymorphisms. Of these, three...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia Mutated Proteins
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle Proteins

Share to Chromatography, High Pressure Liquid

Share to DNA-Binding Proteins

Share to Genetic Testing

Share to Protein Serine-Threonine Kinases

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 11746755
DOI: 10.1002/em.1072

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening breast cancer patients for ATM mutations and polymorphisms by using denaturing high-performance liquid chromatography.PMID 11746755Read ↗

Screening for ATM sequence alterations in African-American women diagnosed with breast cancer.Semantic proximity Read ↗

Spectrum of ATM gene mutations in a hospital-based series of unselected breast cancer patients.Semantic proximity Read ↗

The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers.Semantic proximity Read ↗

Rare variants in the ATM gene and risk of breast cancer.Semantic proximity Read ↗

ATM germline mutations in Spanish early-onset breast cancer patients negative for BRCA1/BRCA2 mutations.Semantic proximity Read ↗

Identification of germline missense mutations and rare allelic variants in the ATM gene in early-onset breast cancer.Semantic proximity Read ↗

Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls.Semantic proximity Read ↗

ATM germline mutations in women with familial breast cancer and a relative with haematological malignancy.Semantic proximity Read ↗

The relationship between twenty missense ATM variants and breast cancer risk: the Multiethnic Cohort.Semantic proximity Read ↗

Increased frequency of ATM mutations in breast carcinoma patients with early onset disease and positive family history.Semantic proximity Read ↗

Ataxia-telangiectasia gene (ATM) mutation heterozygosity in breast cancer: a narrative review.Semantic proximity Read ↗

Rare variants of ATM and risk for Hodgkin's disease and radiation-associated breast cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.