Article
Toll-like receptor 4-mediated activation of murine mast cells.
Journal of leukocyte biology - 1 Dec 2001
McCurdy J D, Lin T J, Marshall J S
Abstract excerpt
Toll-like receptors (TLRs) are a family of pattern recognition receptors that are critical for cellular responses to a variety of bacterial, viral, and fungal products. Mast cells are important to host survival in a number of models of bacterial infection and might act as sentinel cells in host defense. We therefore examined the expression of TLRs and associated molecules by murine bone marrow-derived mast cells...
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