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Article

Interdomain interactions in hinge-bending transitions.

Structure (London, England : 1993) - 1 Dec 2001

Sinha N, Kumar S, Nussinov R

Abstract excerpt

BACKGROUND: The mechanisms that allow or constrain protein movement have not been understood. Here we study interdomain interactions in proteins to investigate hinge-bending motions. RESULTS: We find a limited number of salt bridges and hydrogen bonds at the interdomain interface, in both the "closed" and the "open" conformations. Consistently, analysis of 222 salt bridges in an independently selected database...

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Identifiers

PMID: 11738043
DOI: 10.1016/s0969-2126(01)00687-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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