Article
A hormone-dependent post-translationally regulated mutant for investigating type I cadherin function.
The International journal of developmental biology - 1 Oct 2001
Giacomello E, Morali O, Vallin J, Thiery J P, Broders F
Abstract excerpt
Type I cadherins are Ca2+-dependent cell adhesion molecules. Their function in early Xenopus laevis development has been extensively studied in recent years, by injecting synthetic mRNAs encoding dominant negative mutants with deletions of the extracellular domain into embryos. However, studies at post-gastrula stages have been hampered by the inabilityto progress through post-gastrula development in embryos...
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